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CS-W001157 4
Total: USD 88.00

(R)-2-((tert-Butoxycarbonyl)amino)-3-(3-chlorophenyl)propanoic acid

  • CAS No. 80102-25-6

  • Cat. No. CS-W012137
  • Purity≥98%
  • MDL No.MFCD00672516

*For research and further manufacturing use only, not for direct human use.

(R)-2-((tert-Butoxycarbonyl)amino)-3-(3-chlorophenyl)propanoic acid|CS-W012137

Structure of 80102-25-6

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General Information

  • CAS No. 80102-25-6
  • Cat. No. CS-W012137
  • Purity ≥98%
  • MDL No. MFCD00672516
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₈ClNO₄
  • Molecular Weight 299.75
  • Synonym(s) Boc-D-3-Chlorophenylalanine
  • SMILES O=C(O)[C@@H](CC1=CC=CC(Cl)=C1)NC(OC(C)(C)C)=O

Description

(R)-2-((tert-Butoxycarbonyl)amino)-3-(3-chlorophenyl)propanoic acid is a chiral building block featuring a protected amino group and a para-chlorinated aromatic moiety. This bench-stable derivative integrates seamlessly into peptide synthesis workflows, where the tert-butoxycarbonyl group enables orthogonal protection. The molecule’s electron-deficient phenyl ring enhances reactivity in coupling reactions, supporting efficient access to bioactive scaffolds.

Application

(R)-2-((tert-Butoxycarbonyl)amino)-3-(3-chlorophenyl)propanoic acid serves as a valuable chiral building block in peptide synthesis and medicinal chemistry. The protected α-amino acid functionality enables straightforward deprotection and coupling under standard conditions, while the 3-chlorophenyl group provides a handle for further functionalization. Bench-stable and readily purified by chromatography, it facilitates efficient access to bioactive scaffolds and peptidomimetics.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   2.8604
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   4

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