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Structure of 799274-07-0
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5-Fluoro-1,2,3,4-tetrahydroisoquinoline hydrochloride is a bench-stable, moisture-tolerant heterocyclic amine featuring a fluorinated aromatic ring fused to a saturated nitrogen-containing core. This structure delivers enhanced metabolic stability and improved membrane permeability, enabling efficient incorporation into bioactive molecules for medicinal chemistry campaigns.
5-Fluoro-1,2,3,4-tetrahydroisoquinoline hydrochloride serves as a valuable building block in medicinal chemistry, enabling efficient access to bioactive isoquinoline scaffolds. Its fluorinated aromatic core enhances metabolic stability and modulates electronic properties, while the protonated amine facilitates salt formation for improved solubility and handling. The compound exhibits robust bench stability and functions effectively in standard coupling reactions, including reductive amination and electrophilic substitution, supporting diverse downstream derivatization.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: