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Structure of 79775-07-8
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H-Hyp(tBu)-OH is a bench-stable, moisture-tolerant hypervalent iodine reagent featuring a tert-butyl-substituted hypervalent iodine center. This configuration enhances both stability and reactivity in oxidative transformations, enabling efficient functionalization of nucleophiles under mild conditions.
H-Hyp(tBu)-OH serves as a stable, bench-ready building block for the synthesis of peptide-based inhibitors and bioactive heterocycles. The tert-butyl-protected hydroxyproline moiety enables reliable incorporation into peptidomimetics, offering enhanced solubility and metabolic stability. Its orthogonal protection facilitates sequential coupling in complex fragment assembly, while the hydroxyl group provides a versatile handle for derivatization via standard esterification or ether formation protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: