Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4,5-Dimethylthiazole-2-carboxylic acid

  • CAS No. 79312-41-7

  • Cat. No. CS-0186918
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4,5-Dimethylthiazole-2-carboxylic acid|CS-0186918

Structure of 79312-41-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 79312-41-7
  • Cat. No. CS-0186918
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇NO₂S
  • Molecular Weight 157.19
  • Synonym(s) 2-thiazolecarboxylic acid,4,5-dimethyl
  • SMILES CC1=C(C)SC(=N1)C(=O)O

Description

4,5-Dimethylthiazole-2-carboxylic acid features a fused thiazole core with methyl groups at the 4- and 5-positions, enhancing steric shielding and metabolic stability. The carboxylic acid moiety enables direct conjugation or salt formation, facilitating integration into pharmaceutical scaffolds and bioactive molecules under standard conditions.

Application

4,5-Dimethylthiazole-2-carboxylic acid serves as a versatile building block in medicinal chemistry and heterocyclic synthesis. Its structure enables direct functionalization at the carboxylic acid group for amide bond formation, esterification, or activation via common coupling reagents. The thiazole core exhibits enhanced metabolic stability and favorable pharmacophoric properties, making it suitable for constructing bioactive scaffolds. The methyl substituents provide steric and electronic tuning, while the compound demonstrates good bench stability and ease of purification in standard workflows.

Synthesis

  • Route1
    • 4,5-Dimethylthiazole, ≥97%|CS-1268686
      3581-91-7
    • null|null
      124-38-9
    • ~%
    • In-stock
      4,5-Dimethylthiazole-2-carboxylic acid|CS-0186918
      79312-41-7

    References

    • Tetrahedron Letters, , vol. 26, # 44 p. 5457 - 5458
  • Route2
    • Ethyl 4,5-dimethylthiazole-2-carboxylate|CS-0361554
      79247-96-4
    • ~%
    • In-stock
      4,5-Dimethylthiazole-2-carboxylic acid|CS-0186918
      79312-41-7

    References

    • Helvetica Chimica Acta, , vol. 31, p. 652,662

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.45814
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4,5-Dimethylthiazole-2-carboxylic acid sigma4,5-Dimethylthiazole-2-carboxylic acid manufacturer4,5-Dimethylthiazole-2-carboxylic acid price4,5-Dimethylthiazole-2-carboxylic acid structure4,5-Dimethylthiazole-2-carboxylic acid SDSbuy 4,5-Dimethylthiazole-2-carboxylic acid4,5-Dimethylthiazole-2-carboxylic acid supplier4,5-Dimethylthiazole-2-carboxylic acid uses4,5-Dimethylthiazole-2-carboxylic acid molecular weightprice of 4,5-Dimethylthiazole-2-carboxylic acid4,5-Dimethylthiazole-2-carboxylic acid chemical name formula of 4,5-Dimethylthiazole-2-carboxylic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label