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Structure of 1457-59-6
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4-Methyl-1H-imidazole-5-carboxylic acid features a methyl-substituted imidazole core with a carboxylic acid at the C5 position, offering enhanced solubility and stability under standard conditions. This scaffold integrates readily into bioactive molecule design, particularly in kinase inhibitors and medicinal chemistry libraries. The electron-rich heterocycle supports efficient coupling reactions, enabling streamlined synthesis of targeted compounds.
4-Methyl-1H-imidazole-5-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of imidazole-containing pharmaceuticals and bioactive heterocycles. Its carboxylic acid functionality facilitates direct amidation, esterification, and coupling reactions, while the methyl group enhances metabolic stability and modulates electronic properties. The compound exhibits good bench stability and is compatible with standard peptide coupling protocols, making it suitable for use in high-throughput library synthesis and process-scale applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: