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CS-W001157 4
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2-Bromo-3-methylpyridin-4-amine

  • CAS No. 79055-61-1

  • Cat. No. CS-0106174
  • Purity≥98%
  • MDL No.MFCD20720063

*For research and further manufacturing use only, not for direct human use.

2-Bromo-3-methylpyridin-4-amine|CS-0106174

Structure of 79055-61-1

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General Information

  • CAS No. 79055-61-1
  • Cat. No. CS-0106174
  • Purity ≥98%
  • MDL No. MFCD20720063
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇BrN₂
  • Molecular Weight 187.04
  • Synonym(s) 2-BroMo-3-Methyl-4-pyridinaMine
  • SMILES NC1=C(C)C(Br)=NC=C1

Description

2-Bromo-3-methylpyridin-4-amine features a bromine substituent at the 2-position and a methyl group at the 3-position on a pyridine core bearing a primary amine at the 4-position. This electron-deficient heterocycle serves as a key intermediate in medicinal chemistry, enabling direct functionalization via palladium-catalyzed cross-coupling. The molecule exhibits bench-stable handling and compatibility with standard reaction conditions.

Application

2-Bromo-3-methylpyridin-4-amine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its reactive bromine and amine functionalities. The methyl group provides steric and electronic modulation, while the pyridine core offers compatibility with standard heterocyclic synthesis protocols. Bench-stable and readily purified, it facilitates efficient construction of complex nitrogen-containing scaffolds relevant to API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   1.73472
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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