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CS-W001157 4
Total: USD 88.00

DL-Pantolactone

  • CAS No. 79-50-5

  • Cat. No. CS-0046126
  • Purity≥95%
  • MDL No.MFCD00064333

*For research and further manufacturing use only, not for direct human use.

DL-Pantolactone|CS-0046126

Structure of 79-50-5

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General Information

  • CAS No. 79-50-5
  • Cat. No. CS-0046126
  • Purity ≥95%
  • MDL No. MFCD00064333
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₀O₃
  • Molecular Weight 130.14
  • Synonym(s) None
  • SMILES O=C1OCC(C)(C)C1O

Description

.

Application

DL-Pantolactone serves as a key chiral building block in synthetic organic chemistry, enabling efficient access to pantoyl-containing motifs found in coenzyme Q biosynthesis and related bioactive scaffolds. Its lactone functionality facilitates regioselective derivatization under mild conditions, while the pendant hydroxyl group offers orthogonal reactivity for protection or functionalization. The compound exhibits excellent bench stability and is compatible with standard purification protocols, making it a practical choice for iterative synthesis campaigns in medicinal chemistry and process development.

Synthesis

  • Route1

    References

    • Fuchikami, Takamasa; Ubukata, Yumiko; Tanaka, Yasutaka Tetrahedron Letters, 1991 , vol. 32, # 9 p. 1199 - 1202
  • Route2
    • 2,4-Dihydroxy-3,3-dimethylbutanamide|CS-0364947
      4417-86-1
    • ~40%
    • 3-Hydroxy-4,4-dimethylpyrrolidin-2-one|CS-0310596
      70006-38-1
    • In-stock
      DL-Pantolactone|CS-0046126
      79-50-5

    References

    • Tetrahedron, , vol. 59, # 11 p. 1971 - 1979
  • Route3
    • null|null
      134734-33-1
    • ~91%
    • In-stock
      DL-Pantolactone|CS-0046126
      79-50-5

    References

    • Kinoshita; Hirano; Miyake Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 3 p. 619 - 624

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   -0.0697
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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