Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

(S)-3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one

  • CAS No. 5405-40-3

  • Cat. No. CS-W013437
  • Purity≥97%
  • MDL No.MFCD00216625

*For research and further manufacturing use only, not for direct human use.

(S)-3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one|CS-W013437

Structure of 5405-40-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 5405-40-3
  • Cat. No. CS-W013437
  • Purity ≥97%
  • MDL No. MFCD00216625
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₀O₃
  • Molecular Weight None
  • Synonym(s) S(+)-3,3-DIMETHYL-2-HYDROXY-GAMMA-BUTYROLACTONE
  • SMILES O=C1OCC(C)(C)[C@@H]1O

Description

(S)-3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one is a chiral synthon featuring a stereogenic center at the C3 position and a hydroxyl group flanked by a geminal dimethyl substitution. This configuration imparts enhanced stability and predictable reactivity in asymmetric synthesis. The molecule integrates readily into complex frameworks through selective transformations at the carbonyl and hydroxyl functionalities. Its bench-stable nature facilitates handling under standard conditions.

Application

(S)-3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one serves as a versatile chiral building block in medicinal chemistry, enabling stereoselective synthesis of bioactive molecules. Its constrained cyclic structure supports efficient functionalization at the C3 hydroxyl and C4 quaternary center, with demonstrated compatibility in standard coupling and oxidation reactions. Bench-stable and amenable to purification via chromatography or recrystallization, it functions effectively in multi-step syntheses of heterocyclic scaffolds and natural product analogs.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H318-H303
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   46.53
  • LogP   -0.0697
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5405-40-3 sigma5405-40-3 manufacturer5405-40-3 price5405-40-3 structure5405-40-3 SDSbuy 5405-40-35405-40-3 supplier5405-40-3 uses5405-40-3 molecular weightprice of 5405-40-35405-40-3 chemical name formula of 5405-40-3
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label