3-Methyl-4-nitrobenzene-1-sulfonyl chloride

Name: 3-Methyl-4-nitrobenzene-1-sulfonyl chloride
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 78726-75-7
Cat. No. CS-0261264
Purity≥97%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-Methyl-4-nitrobenzene-1-sulfonyl chloride|CS-0261264

Structure of 78726-75-7

Size

Price

Quantity

* Please select Quantity before adding items.

Description

3-Methyl-4-nitrobenzene-1-sulfonyl chloride features a nitro group at the para position relative to the sulfonyl chloride, enhancing electrophilicity for efficient amine coupling. The methyl substituent provides steric and electronic modulation, improving solubility and reaction control in synthetic transformations. This reagent enables direct sulfonamide formation under mild conditions, offering a robust route to functionalized aromatic scaffolds in medicinal chemistry and materials science.

Application

3-Methyl-4-nitrobenzene-1-sulfonyl chloride serves as a versatile sulfonylating agent for the selective introduction of sulfonamide functionalities under mild conditions. Its electron-withdrawing nitro and methyl groups enhance electrophilicity at the sulfonyl center, enabling efficient coupling with amines and alcohols. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for use in medicinal chemistry campaigns and heterocycle synthesis.

General Information

CAS No. 78726-75-7
Cat. No. CS-0261264
Purity ≥97%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₆ClNO₄S
Molecular Weight 235.64
Synonym(s) None
SMILES O=S(C1=CC=C([N+]([O-])=O)C(C)=C1)(Cl)=O

Computational Chemistry Data

TPSA 77.28
LogP 1.83072
H_Acceptors 4
H_Donors 0
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05
Signal Word : Danger	UN#: 3261
Class : 8	Packing Group : Ⅲ
Hazard Statements : H314-H335
Precautionary Statements : P260-P264-P271-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Nitro compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

78726-75-7 sigma78726-75-7 manufacturer78726-75-7 price78726-75-7 structure78726-75-7 SDSbuy 78726-75-778726-75-7 supplier78726-75-7 uses78726-75-7 molecular weightprice of 78726-75-778726-75-7 chemical name formula of 78726-75-7

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

3-Methyl-4-nitrobenzene-1-sulfonyl chloride

CAS No. 78726-75-7

Recommended Products