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CS-W001157 4
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1-Methylpyrrolidin-3-onehydrochloride

  • CAS No. 78635-85-5

  • Cat. No. CS-0172438
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-Methylpyrrolidin-3-onehydrochloride|CS-0172438

Structure of 78635-85-5

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General Information

  • CAS No. 78635-85-5
  • Cat. No. CS-0172438
  • Purity ≥97%
  • MDL No. None
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₀ClNO
  • Molecular Weight 135.59
  • Synonym(s) 1-Methylpyrrolidin-3-one hydrochloride
  • SMILES CN1CCC(=O)C1.Cl

Description

1-Methylpyrrolidin-3-one hydrochloride is a bench-stable, moisture-tolerant heterocyclic amine salt featuring a polar carbonyl group and a tertiary nitrogen. This structure enables efficient coupling in synthetic transformations, particularly in peptide bond formation and medicinal chemistry applications. Its solubility profile supports use in aqueous and organic media under standard conditions.

Application

1-Methylpyrrolidin-3-one hydrochloride serves as a stable, bench-ready building block for the synthesis of bioactive heterocycles and medicinal chemistry intermediates. Its well-defined reactivity enables efficient incorporation into diverse scaffolds via nucleophilic substitution or reductive amination. The hydrochloride salt enhances solubility and handling, facilitating purification and scalability in standard synthetic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P264-P302+P352-P304+P340

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Computational Chemistry Data

  • TPSA   20.31
  • LogP   0.3128
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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