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CS-W001157 4
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2-Amino-2-(4-bromophenyl)ethan-1-ol

  • CAS No. 201403-02-3

  • Cat. No. CS-0088141
  • Molecule weight216.08
  • Purity≥98%
  • MDL No.MFCD12782005

*For research and further manufacturing use only, not for direct human use.

2-Amino-2-(4-bromophenyl)ethan-1-ol|CS-0088141

Structure of 201403-02-3

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General Information

  • CAS No. 201403-02-3
  • Cat. No. CS-0088141
  • Purity ≥98%
  • MDL No. MFCD12782005
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀BrNO
  • Molecular Weight 216.08
  • Synonym(s) b-AMino-4-broMobenzeneethanol
  • SMILES BrC1=CC=C(C(N)CO)C=C1

Description

2-Amino-2-(4-bromophenyl)ethan-1-ol features a benzylic alcohol scaffold bearing a para-brominated phenyl ring and a primary amine group, enabling integration into pharmaceutical intermediates. This bench-stable compound facilitates synthetic access to bioactive molecules through nucleophilic substitution or coupling reactions under standard conditions.

Application

2-Amino-2-(4-bromophenyl)ethan-1-ol serves as a valuable building block in medicinal chemistry, enabling the synthesis of biologically active heterocycles and functionalized arylamines. Its pendant hydroxyl and primary amine groups offer orthogonal reactivity for derivatization, while the para-bromo substituent facilitates palladium-catalyzed cross-coupling reactions. The compound exhibits good bench stability and is readily purified by recrystallization, supporting its use in multi-step synthetic sequences and API intermediate development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   1.4412
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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