Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Diethyl 2-(4-amino-3-fluorophenyl)-2-methylmalonate

  • CAS No. 78543-08-5

  • Cat. No. CS-0523309
  • Molecule weight283.30
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Diethyl 2-(4-amino-3-fluorophenyl)-2-methylmalonate|CS-0523309

Structure of 78543-08-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 78543-08-5
  • Cat. No. CS-0523309
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₈FNO₄
  • Molecular Weight 283.30
  • Synonym(s) Diethyl (4-amino-3-fluorophenyl)methylmalonate
  • SMILES O=C(OCC)C(C)(C1=CC=C(N)C(F)=C1)C(OCC)=O

Synthesis

  • Route1
    • Diethyl 2-(3-fluoro-4-nitrophenyl)-2-methylmalonate|CS-0672019
      78543-06-3
    • ~97%
    • Diethyl 2-(4-amino-3-fluorophenyl)-2-methylmalonate|CS-0523309
      78543-08-5

    References

    • GLAXO GROUP LIMITED; ALDER, Catherine, Mary; BALDWIN, Ian, Robert; BARTON, Nicholas, Paul; CAMPBELL, Amanda, Jennifer; CHAMPIGNY, Aurelie, Cecile; HARLING, John, David; MAXWELL, Aoife, Caitriona; SIMPSON, Juliet, Kay; SMITH, Ian, Edward, David; TAME, Christopher, John; WILSON, Caroline; WOOLVEN, James, Michael Patent: WO2010/106016 A1, 2010 ; Location in patent: Page/Page column 117 ; WO 2010/106016 A1
  • Route2

    References

    • Peretto, Ilaria; Radaelli, Stefano; Parini, Carlo; Zandi, Michele; Raveglia, Luca F.; Dondio, Giulio; Fontanella, Laura; Misiano, Paola; Bigogno, Chiara; Rizzi, Andrea; Riccardi, Benedetta; Biscaioli, Marcello; Marchetti, Silvia; Puccini, Paola; Catinella, Silvia; Rondelli, Ivano; Cenacchi, Valentina; Bolzoni, Pier Tonino; Caruso, Paola; Villetti, Gino; Facchinetti, Fabrizio; Del Giudice, Elda; Moretto, Nadia; Imbimbo, Bruno P. Journal of Medicinal Chemistry, 2005 , vol. 48, # 18 p. 5705 - 5720
  • Route3

    References

    • Peretto, Ilaria; Radaelli, Stefano; Parini, Carlo; Zandi, Michele; Raveglia, Luca F.; Dondio, Giulio; Fontanella, Laura; Misiano, Paola; Bigogno, Chiara; Rizzi, Andrea; Riccardi, Benedetta; Biscaioli, Marcello; Marchetti, Silvia; Puccini, Paola; Catinella, Silvia; Rondelli, Ivano; Cenacchi, Valentina; Bolzoni, Pier Tonino; Caruso, Paola; Villetti, Gino; Facchinetti, Fabrizio; Del Giudice, Elda; Moretto, Nadia; Imbimbo, Bruno P. Journal of Medicinal Chemistry, 2005 , vol. 48, # 18 p. 5705 - 5720

Safety Information

Download SDS
GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   78.62
  • LogP   1.7918
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   5

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 78543-08-5 sigma78543-08-5 manufacturer78543-08-5 price78543-08-5 structure78543-08-5 SDSbuy 78543-08-578543-08-5 supplier78543-08-5 uses78543-08-5 molecular weightprice of 78543-08-578543-08-5 chemical name formula of 78543-08-5
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label