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Structure of 784-57-6
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2-Morpholino-5-(trifluoromethyl)aniline features a morpholino group attached to an electron-deficient aniline scaffold, enabling strong π-stacking and hydrogen-bonding interactions. This trifluoromethyl-substituted aryl amine integrates readily into pharmaceutical scaffolds, offering enhanced metabolic stability and membrane permeability under standard conditions.
2-Morpholino-5-(trifluoromethyl)aniline serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the morpholine moiety provides hydrogen-bonding capacity and solubility. The compound exhibits good bench stability and functions effectively in standard coupling reactions, facilitating efficient construction of complex scaffolds under routine conditions.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302+H312-H315-H319-H331-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: