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CS-W001157 4
Total: USD 88.00

Indoline-2-carboxylic acid

  • CAS No. 78348-24-0

  • Cat. No. CS-M2631
  • Purity≥98%
  • MDL No.MFCD00010635

*For research and further manufacturing use only, not for direct human use.

Indoline-2-carboxylic acid|CS-M2631

Structure of 78348-24-0

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General Information

  • CAS No. 78348-24-0
  • Cat. No. CS-M2631
  • Purity ≥98%
  • MDL No. MFCD00010635
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉NO₂
  • Molecular Weight 163.17
  • Synonym(s) Indoline-2-carboxylicacid
  • SMILES O=C(O)C1NC2=C(C1)C=CC=C2

Description

Indoline-2-carboxylic acid serves as a key heterocyclic scaffold in medicinal chemistry, offering a rigid, electron-rich core that integrates readily into bioactive molecules. This bench-stable derivative features a fused indoline ring with a carboxylic acid at the C2 position, enabling direct conjugation or derivatization under standard conditions. Its structural integrity supports applications in drug discovery and peptide mimetics.

Application

Indoline-2-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the construction of biologically relevant heterocyclic scaffolds. Its fused indoline core provides structural rigidity and favorable pharmacokinetic properties, while the carboxylic acid functionality facilitates direct derivatization via amide coupling, esterification, or activation for peptide synthesis. The compound exhibits good bench stability and is compatible with a range of standard reaction conditions, making it well-suited for iterative synthesis campaigns in API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H317-H361
Precautionary Statements : P261-P272-P280-P302+P352-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   49.33
  • LogP   1.1078
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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