(2R,4R)-1-tert-Butyl 2-methyl 4-aminopiperidine-1,2-dicarboxylate

Name: (2R,4R)-1-tert-Butyl 2-methyl 4-aminopiperidine-1,2-dicarboxylate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 778646-95-0
Cat. No. CS-0311475
Purity≥98%
MDL No.MFCD18071303

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(2R,4R)-1-tert-Butyl 2-methyl 4-aminopiperidine-1,2-dicarboxylate|CS-0311475

Structure of 778646-95-0

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 778646-95-0
Cat. No. CS-0311475
Purity ≥98%
MDL No. MFCD18071303
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₂H₂₂N₂O₄
Molecular Weight 258.31
Synonym(s) 1-tert-Butyl 2-methyl 4-aminopiperidine-1,2-dicarboxylate
SMILES O=C(N1[C@@H](C(OC)=O)C[C@H](N)CC1)OC(C)(C)C

Description

This chiral piperidine derivative features a tert-butyl-protected amine and methyl-substituted backbone, enabling straightforward functionalization in asymmetric synthesis. The (2R,4R) stereochemistry ensures high diastereoselectivity in downstream transformations, while the dicarboxylate moiety facilitates selective derivatization under mild conditions.

Application

(2R,4R)-1-tert-Butyl 2-methyl 4-aminopiperidine-1,2-dicarboxylate serves as a stereochemically defined chiral building block for the synthesis of bioactive piperidine derivatives. The protected amine and dicarboxylate groups enable selective functionalization and orthogonal transformations. Its bench-stable nature and compatibility with standard coupling reactions facilitate efficient access to complex heterocyclic scaffolds in medicinal chemistry campaigns.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 81.86
LogP 0.8862
H_Acceptors 5
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Amine

Building Blocks Functional Group Ester

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Key Words

778646-95-0 sigma778646-95-0 manufacturer778646-95-0 price778646-95-0 structure778646-95-0 SDSbuy 778646-95-0778646-95-0 supplier778646-95-0 uses778646-95-0 molecular weightprice of 778646-95-0778646-95-0 chemical name formula of 778646-95-0

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

(2R,4R)-1-tert-Butyl 2-methyl 4-aminopiperidine-1,2-dicarboxylate

CAS No. 778646-95-0

Recommended Products