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Structure of 1386457-97-1
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This chiral pyrrolidine derivative features a tert-butoxycarbonyl-protected amine and a methoxy-substituted carbon, enabling direct incorporation into peptide synthesis. The (2S,3R) stereochemistry ensures high diastereoselectivity in coupling reactions, while the bench-stable, moisture-tolerant nature simplifies handling under standard conditions.
(2S,3R)-1-[(tert-butoxy)carbonyl]-3-methoxypyrrolidine-2-carboxylic acid serves as a versatile chiral building block for the synthesis of pyrrolidine-based scaffolds in medicinal chemistry. Its tert-butyl carbamate (Boc) group enables stable protection of the nitrogen, while the methoxy substituent at C3 provides defined stereochemical control and enhances solubility. The carboxylic acid functionality facilitates direct coupling reactions or derivatization under standard peptide conditions, offering robust utility in multi-step syntheses requiring orthogonal functional group handling.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: