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CS-W001157 4
Total: USD 88.00

Biotin alkyne

  • CAS No. 773888-45-2

  • Cat. No. CS-0167789
  • Molecule weight281.37
  • Purity≥97%
  • MDL No.MFCD28385487

*For research and further manufacturing use only, not for direct human use.

Biotin alkyne|CS-0167789

Structure of 773888-45-2

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General Information

  • CAS No. 773888-45-2
  • Cat. No. CS-0167789
  • Purity ≥97%
  • MDL No. MFCD28385487
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₉N₃O₂S
  • Molecular Weight 281.37
  • Synonym(s) None
  • SMILES O=C(NCC#C)CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O

Description

Biotin alkyne enables site-specific conjugation in bioorthogonal labeling workflows. This functionalized probe integrates a reactive alkyne group with high-affinity biotin binding, facilitating efficient capture and detection of modified biomolecules under physiological conditions.

Application

Biotin alkyne serves as a versatile bioorthogonal probe for site-specific labeling and affinity purification. Its terminal alkyne group enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC), facilitating conjugation to azide-functionalized biomolecules with high selectivity. The biotin moiety provides robust streptavidin-binding capability, enabling detection, isolation, or immobilization in pull-down assays and surface-based analyses. Ideal for live-cell labeling and protein tagging applications, it combines excellent bench stability with straightforward purification via streptavidin affinity chromatography.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H317-H319
Precautionary Statements : P261-P264-P272-P280-P302+P352-P362+P364-P501

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Computational Chemistry Data

  • TPSA   70.23
  • LogP   0.4616
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   6

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