3-Chloro-4-iodopyridine

Name: 3-Chloro-4-iodopyridine
Brand: ChemScene
Availability: InStock
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CAS No. 77332-79-7
Cat. No. CS-W002592
Purity≥98%
MDL No.MFCD00272199

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 77332-79-7

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Description

3-Chloro-4-iodopyridine is a halogenated pyridine derivative featuring complementary reactive sites for cross-coupling. The chlorine and iodine substituents enable sequential functionalization, with the iodine group facilitating efficient palladium-catalyzed coupling and the chlorine offering orthogonal reactivity. This dual-halogenation pattern supports modular synthesis in medicinal chemistry and materials science.

Application

3-Chloro-4-iodopyridine serves as a versatile building block in cross-coupling chemistry, enabling efficient construction of substituted pyridine scaffolds. The orthogonal reactivity of the chloro and iodo groups facilitates sequential functionalization via Pd-catalyzed coupling reactions. Its bench-stable nature and compatibility with standard reaction conditions make it well-suited for medicinal chemistry and process development workflows.

General Information

CAS No. 77332-79-7
Cat. No. CS-W002592
Purity ≥98%
MDL No. MFCD00272199
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₃ClIN
Molecular Weight None
Synonym(s) 3-Chlor-4-iodpyridin; 3-Chloro-4-iodopyridine
SMILES ClC1=CN=CC=C1I

Computational Chemistry Data

TPSA 12.89
LogP 2.3396
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07,GHS05
Signal Word : Danger	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P310-P312-P330-P332+P313-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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3-Chloro-4-iodopyridine

CAS No. 77332-79-7

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