Fmoc-L-Norleucine

Name: Fmoc-L-Norleucine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 77284-32-3
Cat. No. CS-W009404
Purity≥98%
MDL No.MFCD00037537

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 77284-32-3

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General Information

CAS No. 77284-32-3
Cat. No. CS-W009404
Purity ≥98%
MDL No. MFCD00037537
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₁H₂₃NO₄
Molecular Weight 353.41
Synonym(s) None
SMILES CCCC[C@@H](C(O)=O)NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O

Description

Fmoc-L-Norleucine features a sterically hindered aliphatic side chain and a bench-stable Fmoc protecting group, enabling efficient incorporation into peptide chains under standard coupling conditions. This derivative supports the synthesis of bioactive peptides with enhanced metabolic stability.

Synthesis

Route1
- 947154-63-4
- ~%
- In-stock
  
  77284-32-3
References
- MONASH UNIVERSITY; WANG, Zhen; ROBINSON, Andrea; SPICCIA, Nicolas Daniel; JACKSON, William Roy Patent: WO2014/5197 A1, 2014 ; Location in patent: Page/Page column 48-49 ;

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 75.63
LogP 4.1685
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 7

Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Leucine and derivatives

Building Blocks Functional Group Fmoc

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Unnatural Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Unnatural Amino Acid Derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids N-Protected Amino Acids

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Fmoc-L-Norleucine

CAS No. 77284-32-3

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