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Structure of 77173-67-2
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Ethyl 4-chloro-8-cyano-3-quinolinecarboxylate features a sterically accessible quinoline core with complementary electron-withdrawing substituents, enabling direct functionalization in transition-metal-catalyzed cross-coupling reactions. The ester group enhances solubility and facilitates downstream derivatization under mild conditions.
3-Quinolinecarboxylic acid, 4-chloro-8-cyano-, ethyl ester serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted quinoline scaffolds. Its compatibility with palladium-catalyzed cross-coupling reactions and tolerance of common functional groups facilitate downstream derivatization. The molecule exhibits good bench stability and simplifies purification, making it well-suited for iterative medicinal chemistry campaigns and process-scale applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: