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Structure of 76444-51-4
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4-Bromo-1-methylpiperidine is a versatile nitrogen-containing heterocycle featuring a bromine substituent at the 4-position and a methyl group on the nitrogen. This configuration imparts enhanced electrophilicity and improved solubility in organic media, facilitating efficient coupling reactions. The molecule exhibits bench-stable handling characteristics and serves as a key intermediate in medicinal chemistry for constructing bioactive scaffolds.
4-Bromo-1-methylpiperidine serves as a versatile building block in medicinal chemistry, enabling efficient construction of nitrogen-containing heterocycles. The bromine at the 4-position provides a reliable site for palladium-catalyzed cross-coupling reactions, while the N-methyl group enhances metabolic stability and modulates basicity. Its bench-stable solid form facilitates handling and purification, making it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: