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CS-W001157 4
Total: USD 88.00

8-Hydroxyoctanoic acid

  • CAS No. 764-89-6

  • Cat. No. CS-0187285
  • Purity≥95%
  • MDL No.MFCD00792446

*For research and further manufacturing use only, not for direct human use.

8-Hydroxyoctanoic acid|CS-0187285

Structure of 764-89-6

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General Information

  • CAS No. 764-89-6
  • Cat. No. CS-0187285
  • Purity ≥95%
  • MDL No. MFCD00792446
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₆O₃
  • Molecular Weight 160.21
  • Synonym(s) None
  • SMILES O=C(O)CCCCCCCO

Description

8-Hydroxyoctanoic acid is a medium-chain hydroxycarboxylic acid featuring a terminal carboxylate and a primary hydroxyl group at the C8 position. This bifunctional scaffold enables direct conjugation or derivatization in synthetic biology and drug delivery applications. The molecule exhibits enhanced solubility in aqueous and organic media, supporting use under standard bench conditions.

Application

8-Hydroxyoctanoic acid serves as a versatile building block for synthesizing bioactive molecules and functionalized polymers. Its bifunctional structure—combining a carboxylic acid and a primary hydroxyl group at C8—enables straightforward derivatization via esterification, ether formation, or lactone cyclization. The compound exhibits good bench stability and facilitates orthogonal functionalization in multi-step syntheses, making it well-suited for applications in medicinal chemistry and materials science.

Synthesis

  • Route1
    • null|null
      5698-29-3
    • ~69%
    • In-stock
      8-Hydroxyoctanoic acid|CS-0187285
      764-89-6

    References

    • Wiberg, Kenneth B.; Waldron, Roy F. Journal of the American Chemical Society, 1991 , vol. 113, # 20 p. 7697 - 7705
  • Route2
    • null|null
      106873-84-1
    • ~73%
    • In-stock
      8-Hydroxyoctanoic acid|CS-0187285
      764-89-6

    References

    • Zhang, Yang; Jiao, Jingliang; Flowers II, Robert A. Journal of Organic Chemistry, 2006 , vol. 71, # 12 p. 4516 - 4520
  • Route3

    References

    • EP2680005 A1, ; Page/Page column ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   57.53
  • LogP   1.4039
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   7

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