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CS-W001157 4
Total: USD 88.00

N-Benzyl-N-Cbz-glycine

  • CAS No. 76315-01-0

  • Cat. No. CS-W003991
  • Purity≥95%
  • MDL No.MFCD02094473

*For research and further manufacturing use only, not for direct human use.

N-Benzyl-N-Cbz-glycine|CS-W003991

Structure of 76315-01-0

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General Information

  • CAS No. 76315-01-0
  • Cat. No. CS-W003991
  • Purity ≥95%
  • MDL No. MFCD02094473
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₉NO₄
  • Molecular Weight None
  • Synonym(s) None
  • SMILES O=C(CN(CC1=CC=CC=C1)C(OC(C)(C)C)=O)O

Description

N-Benzyl-N-Cbz-glycine delivers a protected glycine scaffold with orthogonal functionality, combining a benzyl group for selective deprotection and a Cbz moiety enabling mild acid-labile removal. This bifunctional handle facilitates efficient incorporation into peptide sequences and complex molecular architectures under standard bench conditions.

Application

N-Benzyl-N-Cbz-glycine serves as a versatile di-functional building block for peptide synthesis and heterocycle construction. The Cbz group provides stable protection of the amine, while the benzyl group enables orthogonal deprotection strategies. It facilitates efficient incorporation into peptidomimetics and bioactive scaffolds, offering excellent bench stability, clean reaction profiles, and compatibility with standard coupling protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   66.84
  • LogP   2.5083
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   4

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