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Structure of 76275-86-0
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Methyl 2-(1-hydroxyethyl)thiazole-4-carboxylate features a thiazole core with orthogonal functional handles: a methyl ester for derivatization and a benzylic alcohol enabling selective oxidation or protection. This bench-stable scaffold integrates readily into heterocyclic libraries, serving as a direct precursor to bioactive analogs in medicinal chemistry.
Methyl 2-(1-hydroxyethyl)thiazole-4-carboxylate serves as a versatile synthetic intermediate for thiazole-based scaffolds, enabling straightforward access to functionalized heterocycles via oxidation or substitution. The pendant hydroxymethyl group offers a handle for derivatization, while the methyl ester facilitates subsequent transformations. Its bench-stable nature and compatibility with common reaction conditions make it well-suited for medicinal chemistry campaigns and process-scale synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: