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Ethyl 7-bromo-2-oxo-1,2-dihydroquinoline-4-carboxylate

  • CAS No. 762260-64-0

  • Cat. No. CS-0343274
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Ethyl 7-bromo-2-oxo-1,2-dihydroquinoline-4-carboxylate|CS-0343274

Structure of 762260-64-0

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General Information

  • CAS No. 762260-64-0
  • Cat. No. CS-0343274
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₀BrNO₃
  • Molecular Weight 296.12
  • Synonym(s) 7-bromo-2-oxo-1,2-dihydroquinoline-4-carboxylic acid ethyl ester
  • SMILES O=C(C1=CC(NC2=C1C=CC(Br)=C2)=O)OCC

Synthesis

  • Route1

    References

    • ASTRAZENECA AB Patent: WO2004/81008 A1, 2004 ; Location in patent: Page 64 ; WO 2004/081008 A1
  • Route2
    • In-stock
      7-Bromo-2-oxo-1,2-dihydroquinoline-4-carboxylic acid|CS-0188430
      762260-63-9
    • null|null
      64-17-5
    • ~93%
    • In-stock
      Ethyl 7-bromo-2-oxo-1,2-dihydroquinoline-4-carboxylate|CS-0343274
      762260-64-0

    References

    • CanBas Co., Ltd. Patent: US2008/275057 A1, 2008 ; Location in patent: Page/Page column 74 ;
  • Route3

    References

    • Oza, Vibha; Ashwell, Susan; Brassil, Patrick; Breed, Jason; Ezhuthachan, Jaychandran; Deng, Chun; Grondine, Michael; Horn, Candice; Liu, Dongfang; Lyne, Paul; Newcombe, Nicholas; Pass, Martin; Read, Jon; Su, Mei; Toader, Dorin; Yu, Dingwei; Yu, Yan; Zabludoff, Sonya Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 6 p. 2330 - 2337

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   59.16
  • LogP   2.4673
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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