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Structure of 75867-39-9
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4-((Trimethylsilyl)ethynyl)aniline features a terminal alkyne tethered to an aromatic ring via a silyl-protected acetylene, enabling efficient copper-catalyzed coupling reactions. The trimethylsilyl group enhances stability and facilitates selective deprotection under mild conditions. This boronate moiety integrates seamlessly into complex molecular architectures.
4-((Trimethylsilyl)ethynyl)aniline serves as a versatile building block in cross-coupling and heterocycle synthesis, enabling efficient Sonogashira coupling due to its stable silyl-protected alkyne functionality. The trimethylsilyl group enhances solubility and facilitates selective deprotection, while the aniline moiety supports further derivatization. Its bench stability and compatibility with diverse reaction conditions make it a practical choice for constructing conjugated systems and complex molecular architectures in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335-H413
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Precautionary Statements : P261-P264-P271-P273-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: