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Structure of 7574-67-6
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3-Chloroisoquinolin-1-amine is a heterocyclic amine featuring a chlorine substituent at the 3-position of the isoquinoline core. This electron-deficient scaffold enables direct functionalization in transition-metal-catalyzed couplings, serving as a key building block for pharmaceutical intermediates and bioactive molecule synthesis under standard conditions.
3-Chloroisoquinolin-1-amine serves as a versatile building block in medicinal chemistry, enabling efficient access to isoquinoline-based scaffolds. Its chlorine substituent facilitates palladium-catalyzed cross-coupling reactions, while the primary amine group supports direct functionalization or derivatization. The compound exhibits good bench stability and compatibility with standard protecting group strategies, making it well-suited for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: