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CS-W001157 4
Total: USD 88.00

4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide

  • CAS No. 757251-39-1

  • Cat. No. CS-0006964
  • Molecule weight261.26
  • Purity≥98%
  • MDL No.MFCD09033852

*For research and further manufacturing use only, not for direct human use.

4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide|CS-0006964

Structure of 757251-39-1

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General Information

  • CAS No. 757251-39-1
  • Cat. No. CS-0006964
  • Purity ≥98%
  • MDL No. MFCD09033852
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₂FN₃O₂
  • Molecular Weight 261.26
  • Synonym(s) None
  • SMILES NC1=C(F)C=C(OC2=CC=NC(C(NC)=O)=C2)C=C1

Description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standardsThese Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Synthesis

  • Route1
    • In-stock
      3-Fluoro-4-aminophenol|CS-M1784
      399-95-1
    • 4-Chloro-N-methyl-2-pyridinecarboxamide Sorafenib Impurity|CS-0181543
      220000-87-3
    • ~74%
    • In-stock
      4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide|CS-0006964
      757251-39-1

    References

    • DECIPHERA PHARMACEUTICALS, LLC; FLYNN, Daniel L.; PETILLO, Peter A.; KAUFMAN, Michael D. Patent: WO2013/36232 A2, 2013 ; Location in patent: Paragraph 00220 ;
  • Route2
    • 4-Chloro-N-methyl-2-pyridinecarboxamide Sorafenib Impurity|CS-0181543
      220000-87-3
    • ~%
    • In-stock
      4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide|CS-0006964
      757251-39-1

    References

    • WO2005/9961 A2, ; Page/Page column 46-47 ; WO 2005/009961 A2
  • Route3
    • Phenol, 4-[(1,3-dimethylbutylidene)amino]-3-fluoro-|CS-0010899
      1338722-52-3
    • 4-Chloro-N-methyl-2-pyridinecarboxamide Sorafenib Impurity|CS-0181543
      220000-87-3
    • ~%
    • In-stock
      4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide|CS-0006964
      757251-39-1

    References

    • WO2011/128261 A1, ; Page/Page column 15-16 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS08,GHS09
Signal Word : Warning
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H411
Precautionary Statements : P264-P270-P273-P391-P501

Quality Control

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Computational Chemistry Data

  • TPSA   77.24
  • LogP   1.9548
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   3

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