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CS-W001157 4
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Mal-amido-PEG2-C2-acid

  • CAS No. 756525-98-1

  • Cat. No. CS-M3669
  • Purity≥97%
  • MDL No.MFCD11041136

*For research and further manufacturing use only, not for direct human use.

Mal-amido-PEG2-C2-acid|CS-M3669

Structure of 756525-98-1

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General Information

  • CAS No. 756525-98-1
  • Cat. No. CS-M3669
  • Purity ≥97%
  • MDL No. MFCD11041136
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₀N₂O₇
  • Molecular Weight 328.32
  • Synonym(s) None
  • SMILES O=C(O)CCOCCOCCNC(CCN1C(C=CC1=O)=O)=O

Description

Mal-amido-PEG2-C2-acid features a maleimide group conjugated to a short PEG spacer with a terminal carboxylic acid. This bifunctional linker enables site-specific bioconjugation via thiol-Michael addition, followed by efficient coupling to amine-containing biomolecules. The PEG2 spacer enhances solubility and reduces non-specific binding in aqueous environments.

Application

Mal-amido-PEG2-C2-acid serves as a versatile bifunctional linker for conjugation and polymer chemistry, combining the reactive maleimide group with a carboxylic acid terminus. It enables site-specific bioconjugation via thiol-Michael addition, while the terminal acid facilitates further coupling reactions such as amide formation. The PEG2 spacer provides enhanced solubility and reduced steric hindrance, improving performance in aqueous environments. Ideal for drug delivery systems, peptide-protein conjugates, and surface functionalization applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   122.24
  • LogP   -1.0744
  • H_Acceptors   6
  • H_Donors   2
  • Rotatable_Bonds   12

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