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CS-W001157 4
Total: USD 88.00

1-Cyclobutylethanol

  • CAS No. 7515-29-9

  • Cat. No. CS-W006217
  • Molecule weight100.16
  • Purity≥95%
  • MDL No.MFCD00061039

*For research and further manufacturing use only, not for direct human use.

1-Cyclobutylethanol|CS-W006217

Structure of 7515-29-9

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General Information

  • CAS No. 7515-29-9
  • Cat. No. CS-W006217
  • Purity ≥95%
  • MDL No. MFCD00061039
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂O
  • Molecular Weight 100.16
  • Synonym(s) None
  • SMILES C1(CCC1)C(C)O

Description

1-Cyclobutylethanol offers a rigid cyclobutyl ring fused to an ethanolic side chain, delivering enhanced steric bulk and conformational constraint. This structural profile supports applications in asymmetric synthesis and as a chiral auxiliary, where defined spatial orientation improves stereoselectivity. The molecule exhibits bench-stable handling and moderate solubility in common organic solvents.

Application

1-Cyclobutylethanol serves as a versatile chiral building block in synthetic organic chemistry, offering a rigid cyclobutyl scaffold with a pendant primary alcohol. Its bench-stable nature and compatibility with standard functional group manipulations enable efficient incorporation into complex molecular architectures. The molecule facilitates stereoselective transformations and functions effectively in coupling reactions, protecting group strategies, and heterocycle synthesis, making it valuable for medicinal chemistry and process development workflows.

Synthesis

  • Route1
    • null|null
      3019-25-8
    • ~%
    • In-stock
      1-Cyclobutylethanol|CS-W006217
      7515-29-9

    References

    • Bulletin de la Societe Chimique de France, , p. 600,606
  • Route2
    • null|null
      121416-57-7
    • ~%
    • In-stock
      1-Cyclobutylethanol|CS-W006217
      7515-29-9
    • Trans-(1S,2S)-2-methylcyclopentan-1-ol|CS-0036071
      25144-04-1

    References

    • Tetrahedron, , vol. 45, # 2 p. 443 - 454
  • Route3
    • null|null
      121108-79-0
    • ~%
    • In-stock
      1-Cyclobutylethanol|CS-W006217
      7515-29-9
    • In-stock
      cis-2-Methylcyclopentanol|CS-0036366
      25144-05-2

    References

    • Tetrahedron Letters, , vol. 29, # 51 p. 6753 - 6756

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   1.1673
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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