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CS-W001157 4
Total: USD 88.00

Thiophen-3-amine hydrochloride

  • CAS No. 25475-76-7

  • Cat. No. CS-D0258
  • Purity≥95%
  • MDL No.MFCD11226843

*For research and further manufacturing use only, not for direct human use.

Thiophen-3-amine hydrochloride|CS-D0258

Structure of 25475-76-7

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General Information

  • CAS No. 25475-76-7
  • Cat. No. CS-D0258
  • Purity ≥95%
  • MDL No. MFCD11226843
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₆ClNS
  • Molecular Weight None
  • Synonym(s) 3-aminothiophene hydrochloride
  • SMILES NC1=CSC=C1.Cl

Description

Thiophen-3-amine hydrochloride offers a readily accessible, bench-stable source of the thiophene-3-amine scaffold. This water-soluble salt facilitates efficient incorporation into synthetic sequences requiring nitrogen functionality at the 3-position of thiophene. The protonated amine enhances solubility and handling in aqueous or polar media, streamlining use in medicinal chemistry and materials synthesis workflows.

Application

Thiophen-3-amine hydrochloride serves as a versatile building block in synthetic organic chemistry, enabling direct incorporation of the thiophene scaffold into pharmaceutical and agrochemical intermediates. Its amine functionality facilitates straightforward derivatization via amidation, alkylation, and electrophilic substitution reactions. The hydrochloride salt enhances bench stability and simplifies handling and purification, making it well-suited for scalable synthesis and routine laboratory workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H315-H318-H335
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   1.7521
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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