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Structure of 749875-16-9
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5-Bromo-2-(trifluoromethyl)isonicotinic acid features a trifluoromethyl group at the 2-position and a bromine substituent at the 5-position of the pyridine ring, creating a highly electron-deficient heteroaromatic scaffold. This combination enhances its utility in cross-coupling reactions and as a building block for bioactive molecules. The compound exhibits excellent stability under standard handling conditions and integrates readily into pharmaceutical intermediates.
5-Bromo-2-(trifluoromethyl)isonicotinic acid serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C5 position via cross-coupling reactions. The electron-withdrawing trifluoromethyl group enhances electrophilicity at C4, facilitating nucleophilic substitution and transition-metal-catalyzed transformations. Its bench-stable crystalline form simplifies handling and purification, making it ideal for constructing heterocyclic scaffolds and API intermediates in drug discovery workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: