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Structure of 1070892-04-4
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5-Bromo-2-(trifluoromethyl)isonicotinonitrile features a trifluoromethyl group and a nitrile moiety flanking a bromine substituent on an isonicotinonitrile scaffold. This electron-deficient heteroaromatic system enables direct coupling in cross-coupling reactions, offering high reactivity under standard conditions. The molecule exhibits excellent stability and handles well in synthetic workflows.
5-Bromo-2-(trifluoromethyl)isonicotinonitrile serves as a versatile building block in medicinal chemistry and materials science, enabling palladium-catalyzed cross-coupling reactions due to its dual bromide and nitrile functionalities. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the isonicotinonitrile core provides a rigid, electron-deficient scaffold ideal for constructing heterocyclic APIs and functionalized aromatic systems. Its bench-stable nature and compatibility with standard purification methods facilitate reliable use in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: