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CS-W001157 4
Total: USD 88.00

5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid Lercanidipine Impurity

  • CAS No. 74936-72-4

  • Cat. No. CS-0229090
  • Molecule weight332.31
  • Purity≥98%
  • MDL No.MFCD00475478

*For research and further manufacturing use only, not for direct human use.

5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid Lercanidipine  Impurity|CS-0229090

Structure of 74936-72-4

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General Information

  • CAS No. 74936-72-4
  • Cat. No. CS-0229090
  • Purity ≥98%
  • MDL No. MFCD00475478
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₁₆N₂O₆
  • Molecular Weight 332.31
  • Synonym(s) 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid Monomethyl Ester
  • SMILES O=C(C1=C(C)NC(C)=C(C(OC)=O)C1C2=CC=CC([N+]([O-])=O)=C2)O

Synthesis

  • Route1

    References

    • Zhang, Bang-le; He, Wei; Shi, Xin; Huan, Meng-lei; Huang, Qiu-ju; Zhou, Si-yuan Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 3 p. 805 - 808
  • Route2
    • null|null
      75130-24-4
    • ~88%
    • 5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid Lercanidipine  Impurity|CS-0229090
      74936-72-4

    References

    • Ogawa; Hatayama; Maeda; Kita Chemical and Pharmaceutical Bulletin, 1994 , vol. 42, # 8 p. 1579 - 1589
  • Route3

    References

    • LEK, tovarna farmacevtskih in kemicnih izdelkov, n.sol.o. Patent: US4769465 A1, 1988 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   118.77
  • LogP   2.0872
  • H_Acceptors   6
  • H_Donors   2
  • Rotatable_Bonds   4

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