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Structure of 74785-02-7
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This bromomethylbenzyl alcohol features a reactive bromomethyl group adjacent to a primary hydroxyl, enabling straightforward functionalization. The benzylic position facilitates nucleophilic substitution under mild conditions, while the hydroxyl group offers polarity and hydrogen-bonding capacity. This dual functionality supports efficient derivatization in synthetic sequences.
(2-(Bromomethyl)phenyl)methanol serves as a versatile benzyl building block for C–C and C–heteroatom bond formation. Its bromomethyl group enables direct functionalization via nucleophilic substitution, palladium-catalyzed coupling, or metalation, facilitating the synthesis of biaryl systems and functionalized aryl alcohols. The molecule exhibits good bench stability and compatibility with common protecting groups, making it suitable for iterative synthetic sequences in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS05,GHS07,GHS09
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H302-H314-H317-H410
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Precautionary Statements : P260-P261-P264-P270-P272-P273-P280-P301+P330+P331-P302+P352-P304+P340-P330-P362+P364-P363-P391-P405-P501
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Lot numbers can be found on the outside label of a product: