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CS-W001157 4
Total: USD 88.00

3-Chloro-2-hydroxybenzaldehyde

  • CAS No. 1927-94-2

  • Cat. No. CS-W007724
  • Purity≥96%
  • MDL No.MFCD04973581

*For research and further manufacturing use only, not for direct human use.

3-Chloro-2-hydroxybenzaldehyde|CS-W007724

Structure of 1927-94-2

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General Information

  • CAS No. 1927-94-2
  • Cat. No. CS-W007724
  • Purity ≥96%
  • MDL No. MFCD04973581
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅ClO₂
  • Molecular Weight 156.57
  • Synonym(s) =-chloro-2-hydroxy-BENZALDEHYDE
  • SMILES OC1=C(C=O)C=CC=C1Cl

Description

3-Chloro-2-hydroxybenzaldehyde features a strategically positioned chloro group adjacent to a hydroxyl-bearing aromatic ring, enabling enhanced reactivity in electrophilic substitution and condensation processes. This ortho-hydroxy aldehyde integrates readily into complex heterocyclic scaffolds and serves as a key intermediate in the synthesis of bioactive compounds and functionalized dyes under standard conditions.

Application

3-Chloro-2-hydroxybenzaldehyde serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to bioactive heterocycles. Its ortho-hydroxyl and aldehyde functionalities facilitate intramolecular cyclizations and metal-catalyzed coupling reactions. The chloro substituent enhances electrophilic reactivity and provides a handle for further functionalization, while the compound exhibits good bench stability and ease of purification—ideal for multi-step synthetic sequences.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.8581
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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