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CS-W001157 4
Total: USD 88.00

5,7-Dichloro-2-methylthiazolo[5,4-d]pyrimidine

  • CAS No. 7464-11-1

  • Cat. No. CS-0197406
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5,7-Dichloro-2-methylthiazolo[5,4-d]pyrimidine|CS-0197406

Structure of 7464-11-1

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General Information

  • CAS No. 7464-11-1
  • Cat. No. CS-0197406
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃Cl₂N₃S
  • Molecular Weight 220.08
  • Synonym(s) 3,5-dichloro-8-methyl-9-thia-2,4,7-triazabicyclo[4.3.0]nona-2,4,7,10-tetraene
  • SMILES CC1=NC2=C(Cl)N=C(Cl)N=C2S1

Synthesis

  • Route1
    • 2-Methylthiazolo[5,4-d]pyrimidine-5,7(4H,6H)-dione|CS-1673461
      5021-52-3
    • ~52%
    • 5,7-Dichloro-2-methylthiazolo[5,4-d]pyrimidine|CS-0197406
      7464-11-1

    References

    • F.HOFFMANN-LA ROCHE AG Patent: WO2008/152390 A1, 2008 ; Location in patent: Page/Page column 34; 45-46 ; WO 2008/152390 A1
  • Route2
    • 5-Amino-2-methylthiazole-4-carbonitrile|CS-0517412
      31785-16-7
    • null|null
      503-38-8
    • ~%
    • 5,7-Dichloro-2-methylthiazolo[5,4-d]pyrimidine|CS-0197406
      7464-11-1

    References

    • ASTRAZENECA AB; ASTRAZENECA UK LIMITED; CHUAQUI, Claudio, Edmundo; HUANG, Shan; IOANNIDIS, Stephanos; SHI, Jie; SU, Mei; SU, Qibin Patent: WO2010/38060 A1, 2010 ; Location in patent: Page/Page column 73 ; WO 2010/038060 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   38.67
  • LogP   2.70152
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   0

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