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CS-W001157 4
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Phenyl phosphorodiamidate

  • CAS No. 7450-69-3

  • Cat. No. CS-0206396
  • Purity≥97%
  • MDL No.MFCD00014767

*For research and further manufacturing use only, not for direct human use.

Phenyl phosphorodiamidate|CS-0206396

Structure of 7450-69-3

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General Information

  • CAS No. 7450-69-3
  • Cat. No. CS-0206396
  • Purity ≥97%
  • MDL No. MFCD00014767
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₉N₂O₂P
  • Molecular Weight 172.12
  • Synonym(s) Phosphorodiamidic acid, phenyl ester
  • SMILES C1=CC=C(C=C1)OP(=O)(N)N

Description

Phenyl phosphorodiamidate serves as a robust, bench-stable reagent for phosphoryl transfer reactions. This phosphoramidate moiety integrates readily into nucleoside analogs and peptide conjugates, offering enhanced stability and controlled release in biochemical applications.

Synthesis

  • Route1

    References

    • Archiv der Pharmazie (Weinheim, Germany), , vol. 314, # 1 p. 85 - 91
  • Route2
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      108-95-2
    • ~%
    • Diphenyl phosphoramidate|CS-0090969
      2015-56-7
    • In-stock
      Phenyl phosphorodiamidate|CS-0206396
      7450-69-3

    References

    • Journal of the American Chemical Society, , vol. 63, p. 2117

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   78.34
  • LogP   1.0909
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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