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Structure of 741709-62-6
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4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinecarbonitrile features a boronate ester group coupled to a pyridine ring bearing a nitrile at the ortho position. This combination enables efficient Suzuki-Miyaura coupling under mild conditions, with enhanced stability and moisture tolerance. The electron-deficient pyridine moiety facilitates selective reaction kinetics in cross-coupling processes.
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinecarbonitrile serves as a versatile boronate building block in Suzuki-Miyaura cross-coupling reactions. The pyridinecarbonitrile moiety provides enhanced electronic tuning and ortho-directing capability, while the pinacol boronate ester ensures excellent bench stability, ease of handling, and compatibility with a broad range of transition metal catalysts. This reagent facilitates efficient construction of complex heterocyclic scaffolds and functionalized aryl biaryls under mild reaction conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: