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CS-W001157 4
Total: USD 88.00

Boc-D-Glu-OtBu

  • CAS No. 73872-71-6

  • Cat. No. CS-0131705
  • Purity≥97%
  • MDL No.MFCD00076926

*For research and further manufacturing use only, not for direct human use.

Boc-D-Glu-OtBu|CS-0131705

Structure of 73872-71-6

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General Information

  • CAS No. 73872-71-6
  • Cat. No. CS-0131705
  • Purity ≥97%
  • MDL No. MFCD00076926
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₅NO₆
  • Molecular Weight 303.35
  • Synonym(s) N-Boc-D-glutaMic acid 1-tert-butyl ester
  • SMILES O=C(O)CC[C@H](C(OC(C)(C)C)=O)NC(OC(C)(C)C)=O

Description

Boc-D-Glu-OtBu serves as a protected amino acid building block for peptide synthesis, featuring a stable tert-butoxycarbonyl (Boc) group at the α-amino terminus and a butyl ester at the carboxyl side chain. This configuration enables selective coupling reactions under standard conditions, facilitating efficient incorporation into complex peptide sequences with minimal side reactivity.

Application

Boc-D-Glu-OtBu serves as a stable, bench-ready building block for the synthesis of D-glutamic acid-containing peptides and heterocyclic scaffolds. Its orthogonal protection—tert-butyl ester and Boc group—enables selective deprotection during sequence assembly. The compound exhibits excellent functional group tolerance and facilitates efficient coupling reactions, making it ideal for solid-phase peptide synthesis and medicinal chemistry campaigns requiring D-amino acid incorporation.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   101.93
  • LogP   2.0862
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   5

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