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CS-W001157 4
Total: USD 88.00

3-Fluoropiperidine hydrochloride

  • CAS No. 737000-77-0

  • Cat. No. CS-W001632
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Fluoropiperidine hydrochloride|CS-W001632

Structure of 737000-77-0

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General Information

  • CAS No. 737000-77-0
  • Cat. No. CS-W001632
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₁ClFN
  • Molecular Weight 139.60
  • Synonym(s) None
  • SMILES FC1CCCNC1.Cl

Description

3-Fluoropiperidine hydrochloride is a bench-stable, moisture-tolerant heterocyclic amine featuring a fluorinated piperidine core. This compound integrates readily into medicinal chemistry campaigns, offering enhanced metabolic stability and improved membrane permeability in bioactive molecule design.

Application

3-Fluoropiperidine hydrochloride serves as a versatile building block in medicinal chemistry, enabling the incorporation of a fluorinated piperidine moiety into bioactive molecules. Its well-established stability and ease of handling facilitate efficient functionalization, particularly in amide coupling and reductive amination workflows. The compound functions effectively as a key scaffold component in the synthesis of pharmaceutical intermediates, offering enhanced metabolic stability and modulated basicity compared to non-fluorinated analogs.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.03
  • LogP   1.1297
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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