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CS-W001157 4
Total: USD 88.00

5-Bromo-1H-indazol-3-ol

  • CAS No. 7364-27-4

  • Cat. No. CS-D0107
  • Purity≥97%
  • MDL No.MFCD10697926
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Bromo-1H-indazol-3-ol|CS-D0107

Structure of 7364-27-4

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Description

5-Bromo-1H-indazol-3-ol features a brominated indazol-3-ol scaffold with enhanced electron density at the 3-position, enabling efficient coupling in cross-coupling reactions. The phenolic hydroxyl group supports direct derivatization and facilitates hydrogen bonding interactions in target binding. This bench-stable compound serves as a key intermediate for bioactive molecule synthesis.

Application

5-Bromo-1H-indazol-3-ol serves as a versatile building block for medicinal chemistry and materials science, enabling direct functionalization at the C3 position via palladium-catalyzed cross-coupling. The bromo group facilitates Suzuki, Stille, and Negishi reactions, while the phenolic OH supports derivatization and metal chelation. Its bench-stable crystalline form simplifies handling and purification in multi-step synthesis.

General Information

  • CAS No. 7364-27-4
  • Cat. No. CS-D0107
  • Purity ≥97%
  • MDL No. MFCD10697926
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅BrN₂O
  • Molecular Weight 213.03
  • Synonym(s) 3H-Indazol-3-one, 5-bromo-1,2-dihydro-
  • SMILES O=C1NNC2=C1C=C(Br)C=C2

Computational Chemistry Data

  • TPSA   48.65
  • LogP   1.6187
  • H_Acceptors   1
  • H_Donors   2
  • Rotatable_Bonds   0

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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