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Structure of 73591-69-2
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5-Isopropylnicotinic acid features a sterically hindered isopropyl group at the pyridine ring's 5-position, enhancing metabolic stability and modulating electronic properties. This substitution pattern improves lipophilicity for membrane permeability while maintaining solubility in common organic solvents. The carboxylic acid functionality enables direct coupling reactions for peptide and pharmaceutical synthesis.
5-Isopropylnicotinic acid serves as a valuable building block in medicinal chemistry and agrochemical synthesis, offering a sterically hindered pyridine carboxylic acid scaffold. Its isopropyl group enhances metabolic stability and modulates lipophilicity, while the carboxylic acid functionality enables straightforward derivatization via amide coupling, esterification, or salt formation. The compound exhibits good bench stability and facilitates efficient purification, making it well-suited for use in high-throughput screening campaigns and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: