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CS-W001157 4
Total: USD 88.00

5-Isopropylnicotinic acid

  • CAS No. 73591-69-2

  • Cat. No. CS-0004258
  • Purity≥98%
  • MDL No.MFCD11043004
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Isopropylnicotinic acid|CS-0004258

Structure of 73591-69-2

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Description

5-Isopropylnicotinic acid features a sterically hindered isopropyl group at the pyridine ring's 5-position, enhancing metabolic stability and modulating electronic properties. This substitution pattern improves lipophilicity for membrane permeability while maintaining solubility in common organic solvents. The carboxylic acid functionality enables direct coupling reactions for peptide and pharmaceutical synthesis.

Application

5-Isopropylnicotinic acid serves as a valuable building block in medicinal chemistry and agrochemical synthesis, offering a sterically hindered pyridine carboxylic acid scaffold. Its isopropyl group enhances metabolic stability and modulates lipophilicity, while the carboxylic acid functionality enables straightforward derivatization via amide coupling, esterification, or salt formation. The compound exhibits good bench stability and facilitates efficient purification, making it well-suited for use in high-throughput screening campaigns and process development workflows.

General Information

  • CAS No. 73591-69-2
  • Cat. No. CS-0004258
  • Purity ≥98%
  • MDL No. MFCD11043004
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁NO₂
  • Molecular Weight 165.19
  • Synonym(s) 3-Pyridinecarboxylicacid,5-(1-methylethyl)-(9CI)
  • SMILES O=C(O)C1=CC(C(C)C)=CN=C1

Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.9032
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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