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Structure of 7358-93-2
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3-Cyclopropylprop-2-ynoic acid features a conjugated alkyne-carboxylic acid motif with a cyclopropyl group at the β-position, offering enhanced stability and defined steric profile. This scaffold enables efficient coupling in click chemistry and serves as a key building block for bioconjugation, peptide modification, and the synthesis of functionalized heterocycles under mild conditions.
3-Cyclopropylprop-2-ynoic acid serves as a versatile building block for synthesizing bioactive heterocycles and functionalized alkynes. Its terminal alkyne moiety enables reliable copper-catalyzed azide-alkyne cycloaddition (CuAAC), while the carboxylic acid group facilitates direct derivatization or amide coupling. The cyclopropyl substituent imparts conformational rigidity and enhances metabolic stability, making it valuable in medicinal chemistry scaffolds. Bench-stable and compatible with standard purification protocols, it functions effectively in multi-step synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: