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Structure of 7355-55-7
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7-Deazaguanine features a modified purine scaffold where the nitrogen at position 7 is replaced by carbon, enhancing metabolic stability and altering electronic properties. This structural refinement supports its use in nucleoside analogs for antiviral and anticancer applications, offering improved resistance to enzymatic degradation while maintaining base-pairing fidelity.
7-Deazaguanine serves as a valuable purine scaffold for medicinal chemistry and nucleoside analog synthesis, offering enhanced metabolic stability compared to guanine. Its preserved hydrogen bonding capacity enables incorporation into oligonucleotides and enzymatic substrates, while the absence of the C7 nitrogen improves resistance to oxidation. The compound functions reliably in standard coupling protocols and exhibits favorable bench stability, facilitating straightforward purification and integration into synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: