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CS-W001157 4
Total: USD 88.00

3-(Pyridin-2-yl)acrylic acid

  • CAS No. 7340-22-9

  • Cat. No. CS-W021780
  • Purity≥98%
  • MDL No.MFCD00179422

*For research and further manufacturing use only, not for direct human use.

3-(Pyridin-2-yl)acrylic acid|CS-W021780

Structure of 7340-22-9

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General Information

  • CAS No. 7340-22-9
  • Cat. No. CS-W021780
  • Purity ≥98%
  • MDL No. MFCD00179422
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇NO₂
  • Molecular Weight 149.15
  • Synonym(s) 3-(pyridin-2-yl)prop-2-enoic acid
  • SMILES O=C(O)/C=C/C1=NC=CC=C1

Description

3-(Pyridin-2-yl)acrylic acid features a conjugated system linking a pyridine ring to an acrylic acid moiety, enabling integration into π-extended frameworks. The carboxylic acid group provides a robust handle for derivatization, while the electron-deficient pyridine enhances reactivity in cross-coupling and coordination chemistry. This structure supports applications in ligand design, polymer functionalization, and bioconjugation under standard conditions.

Application

3-(Pyridin-2-yl)acrylic acid serves as a versatile building block for heterocyclic synthesis and conjugated systems, enabling efficient access to bioactive scaffolds. Its conjugated enoic acid functionality facilitates Diels-Alder reactions, Michael additions, and transition-metal-catalyzed coupling processes. The pyridine moiety provides orthogonal reactivity and enhanced solubility, supporting downstream derivatization in medicinal chemistry. Bench-stable and readily purified by recrystallization, it functions reliably in standard synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.1794
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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