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Structure of 70526-11-3
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(E)-Ethyl 3-(pyridin-2-yl)acrylate features a conjugated enoate system linked to a pyridine heterocycle, enabling efficient integration into cross-coupling and cycloaddition workflows. The extended π-system enhances reactivity in transition-metal-catalyzed processes, while the ethyl ester facilitates downstream derivatization. This bench-stable, moisture-tolerant acrylate serves as a key building block for bioactive heterocycles and functional materials.
(E)-Ethyl 3-(pyridin-2-yl)acrylate serves as a versatile synthetic building block in organic and medicinal chemistry, enabling efficient construction of functionalized α,β-unsaturated esters. Its conjugated system facilitates Diels-Alder reactions, Michael additions, and palladium-catalyzed cross-couplings. The pyridyl moiety provides orthogonal reactivity and enhanced solubility, while the (E)-configuration ensures predictable stereochemical outcomes. Bench-stable and readily purified by column chromatography, it functions as a key intermediate in heterocyclic synthesis and API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P280-P304+P340
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Lot numbers can be found on the outside label of a product: