2-Acetamido-4-methylthiazole

Name: 2-Acetamido-4-methylthiazole
Brand: ChemScene
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CAS No. 7336-51-8
Cat. No. CS-W016233
Purity≥98%
MDL No.MFCD00011561

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Description

2-Acetamido-4-methylthiazole features a thiazole core functionalized with an acetamido group at the 2-position and a methyl substituent at the 4-position, delivering enhanced solubility and stability under standard conditions. This scaffold serves as a key building block in medicinal chemistry for accessing bioactive heterocycles.

Application

2-Acetamido-4-methylthiazole serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to thiazole-based scaffolds. Its acetamido group offers a handle for further functionalization, while the methyl substituent enhances stability and modulates reactivity. The compound exhibits excellent bench stability, facilitates straightforward purification, and participates reliably in standard coupling and cyclization protocols, making it well-suited for the synthesis of bioactive molecules and API intermediates.

General Information

CAS No. 7336-51-8
Cat. No. CS-W016233
Purity ≥98%
MDL No. MFCD00011561
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₈N₂OS
Molecular Weight 156.21
Synonym(s) N-(4-Methylthiazol-2-yl)acetamide
SMILES CC1=CSC(NC(C)=O)=N1

Computational Chemistry Data

TPSA 41.99
LogP 1.40992
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Thiazole compounds

Key Words

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2-Acetamido-4-methylthiazole

CAS No. 7336-51-8

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