Boc-D-Pro-OMe

Name: Boc-D-Pro-OMe
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 73323-65-6
Cat. No. CS-W019985
Molecule weight229.28
Purity≥97%
MDL No.MFCD00190828

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 73323-65-6

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 73323-65-6
Cat. No. CS-W019985
Purity ≥97%
MDL No. MFCD00190828
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₁H₁₉NO₄
Molecular Weight 229.28
Synonym(s) N-Boc-D-proline Methyl Ester
SMILES O=C(OC(C)(C)C)N(CCC1)[C@H]1C(OC)=O

Description

Boc-D-Pro-OMe features a protected D-proline moiety with a methyl ester group, enabling direct incorporation into peptide chains without racemization. The Boc group ensures stability during synthesis, while the OMe functionality facilitates efficient coupling under standard conditions. This derivative serves as a key building block in the construction of constrained peptidomimetics and bioactive oligomers.

Application

Boc-D-Pro-OMe serves as a versatile building block in peptide synthesis, enabling efficient incorporation of D-proline residues with enhanced stability and solubility. The Boc group provides reliable protection for the amine, while the methyl ester facilitates straightforward hydrolysis or further derivatization. Its bench-stable nature and compatibility with standard coupling protocols make it ideal for iterative synthesis of cyclic peptides and bioactive scaffolds.

Synthesis

Route1
- 294659-30-6
- ~%
- In-stock
  
  59936-29-7
- In-stock
  
  73323-65-6
References
- Journal of the American Chemical Society, , vol. 130, # 3 p. 808 - 809
Route2
- In-stock
  
  37784-17-1
- 74-88-4
- ~66%
- In-stock
  
  73323-65-6
References
- ZALICUS PHARMACEUTICALS LTD.; PAJOUHESH, Hassan, A.; HOLLAND, Richard; ZHANG, Lingyun; PAJOUHESH, Hossein, O.; LAMONTAGNE, Jason; WHELAN, Brendan; SHORT, Glenn, F., III.; ROMERO, Donna, L. Patent: WO2013/131018 A1, 2013 ; Location in patent: Page/Page column 38 ;
Route3
- In-stock
  
  24424-99-5
- 43041-12-9
- ~%
- In-stock
  
  73323-65-6
References
- US2009/93472 A1, ; Page/Page column 31-32 ; US 20090093472 A1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 55.84
LogP 1.5589
H_Acceptors 4
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Ester

Building Blocks Skeleton Aliphatic heterocycle compounds Pyrrolidine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Proline and derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Amino Acid Derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids C-ProtectedAmino Acids

Biochemistry Biochemicals and Reagents Amino Acids N-Protected Amino Acids

Key Words

Boc-D-Pro-OMe sigmaBoc-D-Pro-OMe manufacturerBoc-D-Pro-OMe priceBoc-D-Pro-OMe structureBoc-D-Pro-OMe SDSbuy Boc-D-Pro-OMeBoc-D-Pro-OMe supplierBoc-D-Pro-OMe usesBoc-D-Pro-OMe molecular weightprice of Boc-D-Pro-OMeBoc-D-Pro-OMe chemical name formula of Boc-D-Pro-OMe

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Boc-D-Pro-OMe

CAS No. 73323-65-6

Recommended Products

General Information

Description

Application

Synthesis

References

References

References

Safety Information

Quality Control

Computational Chemistry Data

Similar Products

Other Classifications

Recently Viewed Products

Key Words