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Structure of 73217-11-5
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This bromomethyl-substituted arylacetonitrile features a reactive bromomethyl group flanked by an electron-withdrawing nitrile, enabling efficient coupling in cross-coupling and functionalization workflows. The pendant phenyl ring provides structural rigidity, enhancing regioselectivity in C–H activation processes. Bench-stable under standard conditions, it serves as a key intermediate in the synthesis of bioactive heterocycles and advanced pharmaceutical scaffolds.
2-(2-(Bromomethyl)phenyl)acetonitrile serves as a versatile synthetic building block for constructing biaryl and heterocyclic scaffolds. The bromomethyl group enables efficient nucleophilic substitution and Pd-catalyzed coupling reactions, while the nitrile functionality offers compatibility with standard functional group transformations. Its bench-stable nature and ease of purification make it well-suited for iterative synthesis in medicinal chemistry and process development workflows.
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H314
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Precautionary Statements : P264-P271-P280-P301+P330+P331-P304+P340-P363-P501
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Lot numbers can be found on the outside label of a product: